STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_1195Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:H64484 AC:H64484, p()=2.1E-24, pid=31%. (222 aa)    
Predicted Functional Partners:
sepS
phenylalanyl-tRNA synthetase alpha subunit; Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys).
   
 
 0.901
MTH_1067
Acetyltransferase; Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L- cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)); Belongs to the SepCysS family.
    
 
 0.879
pheS
phenylalanyl-tRNA synthetase; Function Code:10.07 - Metabolism of Macromolecules, Aminoacyl tRNA synthetases and tRNA modification; similar to, sp:LN:SYF_METJA AC:Q57911, p()=1.9E-93, pid=37%; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
   
 
 0.812
MTH_1194
Acetylpolyamine aminohydolase; Probable deacetylase; Belongs to the histone deacetylase family.
       0.770
MTH_1193
Transcriptional regulator; Function Code:10.02 - Metabolism of Macromolecules, Transcription--mRNA synthesis and modification (includes regulators); similar to, sp:LN:Y151_METJA AC:Q57615, p()=1.7E-13, pid=20%.
       0.643
MTH_867
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:G64484 AC:G64484, p()=4.7E-123, pid=57%.
  
    0.550
pgk2
2-phosphoglycerate kinase; Function Code:1.01 - Carbohydrate Metabolism, Glycolysis--Gluconeogenesis; similar to, pir:LN:S41582 AC:S41582, p()=1.2E-115, pid=69%.
  
    0.493
mptA
Conserved protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
       0.492
MTH_1197
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:C64361 AC:C64361, p()=0.0000022, pid=24%.
       0.492
cofG
Biotin synthetase related protein; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil.
       0.456
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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