STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_1221Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:F64351 AC:F64351, p()=4.4E-72, pid=40%. (381 aa)    
Predicted Functional Partners:
MTH_243
Conserved protein; RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. Belongs to the HARP family.
 
     0.822
MTH_1223
Inosine-5'-monophosphate dehydrogenase related protein II; Function Code:4.01 - Nucleotide Metabolism, Purine metabolism; similar to, pir:LN:H64452 AC:H64452, p()=5.4E-19, pid=45%.
 
     0.757
MTH_1224
Inosine-5'-monophosphate dehydrogenase related protein III; Function Code:4.01 - Nucleotide Metabolism, Purine metabolism; similar to, pir:LN:H64452 AC:H64452, p()=1.1E-48, pid=34%.
       0.755
MTH_1222
Inosine-5'-monophosphate dehydrogenase related protein I; Function Code:4.01 - Nucleotide Metabolism, Purine metabolism; similar to, pir:LN:H64452 AC:H64452, p()=3.6E-22, pid=26%.
       0.721
MTH_1225
Inosine-5'-monophosphate dehydrogenase related protein IV; Function Code:4.01 - Nucleotide Metabolism, Purine metabolism; similar to, pir:LN:H64452 AC:H64452, p()=1.2E-11, pid=21%.
 
     0.696
MTH_1226
Inosine-5'-monophosphate dehydrogenase related protein V; Function Code:4.01 - Nucleotide Metabolism, Purine metabolism; similar to, pir:LN:E64381 AC:E64381, p()=8.5E-37, pid=40%.
       0.630
MTH_1220
Chorismate mutase; Function Code:5.14 - L-Amino Acid Metabolism, Phenylalanine--tyrosine and tryptophan biosynthesis; similar to, sp:LN:PHEA_PSEST AC:P27603, p()=2E-51, pid=42%.
       0.591
MTH_238
Tungsten formylmethanofuran dehydrogenase, subunit C homolog; Function Code:2.02 - Energy Metabolism, Methane metabolism; similar to, pir:LN:B64382 AC:B64382, p()=7.3E-70, pid=31%; To M.jannaschii MJ0658.
  
     0.559
polB1
DNA-dependent DNA polymerase family B (PolB1); In addition to polymerase activity, this DNA polymerase exhibits 3'-5' exonuclease activity; Belongs to the DNA polymerase type-B family.
 
    0.549
MTH_1356
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:F64404 AC:F64404, p()=4.2E-35, pid=36%.
 
     0.539
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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