STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_1252Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:F64398 AC:F64398, p()=0.00000014, pid=16%. (222 aa)    
Predicted Functional Partners:
MTH_1253
Unknown; Function Code:14.00 - Unknown; similar to, sp:LN:DCA1_METFR AC:Q49161, p()=0.87, pid=09%.
       0.728
mre11
Rad32 related protein; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family.
     
 0.677
MTH_495
Modification methyltransferase, cytosine-specific; Function Code:10.11 - Metabolism of Macromolecules, DNA degradation--restriction/modification; similar to, sp:LN:MTD1_DESDN AC:P05302, p()=8.6E-37, pid=30%; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
   
    0.605
MTH_1249
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:Y292_METJA AC:Q57740, p()=2.6E-10, pid=35%.
     
 0.564
MTH_708
Thioredoxin reductase; Function Code:4.02 - Nucleotide Metabolism, Pyrimidine metabolism; similar to, gp_new:GI:e313024:g1945648 LN:BSZ94043, p()=3.8E-57, pid=42%.
     
 0.533
MTH_1247
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:E64463 AC:E64463, p()=4.8E-27, pid=40%.
       0.494
MTH_1248
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:E64354 AC:E64354, p()=2E-12, pid=39%.
       0.494
MTH_1250
Unknown; Function Code:14.00 - Unknown; similar to, pir:LN:F64452 AC:F64452, p()=0.0069, pid=20%.
       0.494
MTH_1251
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:A64419 AC:A64419, p()=3.2E-21, pid=47%.
       0.494
MTH_496
Endonuclease III homolog; Function Code:10.11 - Metabolism of Macromolecules, DNA degradation--restriction/modification; similar to, sp:LN:GTMR_METTF AC:P29588, p()=2.2E-31, pid=30%.
     
 0.450
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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