STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dysDeoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. (307 aa)    
Predicted Functional Partners:
eif5a
Translation initiation factor, eIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
   
 0.987
MTH_128
Unknown; Function Code:14.00 - Unknown; similar to, sp:LN:YPO4_NPVLD AC:P30326, p()=0.97, pid=07%.
       0.897
MTH_126
Inosine-5'-monophosphate dehydrogenase related protein VII; Function Code:4.01 - Nucleotide Metabolism, Purine metabolism; similar to, sp:LN:YC32_METJA AC:Q58629, p()=1.2E-62, pid=41%.
       0.848
top6A
Conserved protein; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family.
 
   
 0.831
rpl6
Ribosomal protein L9 (E.coli); This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
   
 
 0.763
pyrF
Orotidine 5' monophosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
       0.714
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
  
 
 0.710
MTH_868
Agmatine ureohydrolase; Function Code:5.09 - L-Amino Acid Metabolism, Arginine and proline metabolism; similar to, sp:LN:YHMF_METFE AC:P19268, p()=3.9E-64, pid=41%; Belongs to the arginase family.
 
   
 0.696
MTH_1146
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, gp:GI:g726059 LN:MTU19363, p()=8.8E-106, pid=83%.
   
   0.692
tiaS
Conserved protein; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
     
 0.692
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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