STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_1306Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:YC10_METJA AC:Q58607, p()=3E-34, pid=33%. (189 aa)    
Predicted Functional Partners:
MTH_1305
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:Y043_METJA AC:Q60348, p()=3.5E-94, pid=47%.
       0.884
eif2a
Translation initiation factor eIF-2, alpha subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the eIF-2-alpha family.
 
    0.842
nop10
Unknown; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.
       0.806
rpl44e
Ribosomal protein L36a; Binds to the 23S rRNA.
 
     0.783
rps27e
Ribosomal protein S27; Function Code:10.04 - Metabolism of Macromolecules, Ribosomal proteins; similar to, sp:LN:RS27_METJA AC:P54028, p()=2.2E-13, pid=43%.
 
     0.758
MTH_1665
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:E64427 AC:E64427, p()=3.6E-38, pid=33%.
  
     0.628
MTH_164
Single-stranded DNA exonuclease RecJ related protein; Function Code:10.11 - Metabolism of Macromolecules, DNA degradation--restriction/modification; similar to, pir:LN:A64422 AC:A64422, p()=4.9E-57, pid=32%.
  
     0.625
pfdB
Conserved protein; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
  
     0.617
priS
DNA primase, small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...]
 
     0.597
MTH_1324
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:Y039_METJA AC:Q60351, p()=4.2E-19, pid=37%.
 
     0.595
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.