STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpl44eRibosomal protein L36a; Binds to the 23S rRNA. (92 aa)    
Predicted Functional Partners:
rpl30e
Ribosomal protein L30; Function Code:10.04 - Metabolism of Macromolecules, Ribosomal proteins; similar to, sp:LN:RL3E_METJA AC:P54061, p()=7.3E-31, pid=66%; Belongs to the eukaryotic ribosomal protein eL30 family.
   
 0.999
rps12
Ribosomal protein S23 (E.coli); With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family.
   
 
 0.999
rps7
Ribosomal protein S5 (E.coli); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family.
   
 
 0.999
fusA
Translation elongation factor, EF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase [...]
  
 0.999
rps10
Ribosomal protein S20 (E.coli); Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
  
 
 0.999
rpl10e
Ribosomal protein L10; Function Code:10.04 - Metabolism of Macromolecules, Ribosomal proteins; similar to, pir:LN:G64367 AC:G64367, p()=2.3E-50, pid=53%; Belongs to the universal ribosomal protein uL16 family.
 
 0.999
rps17
Ribosomal protein S11 (E.coli); One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
   
 
 0.999
rpl14
Ribosomal protein L23 (E.coli); Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
  
 0.999
rps27e
Ribosomal protein S27; Function Code:10.04 - Metabolism of Macromolecules, Ribosomal proteins; similar to, sp:LN:RS27_METJA AC:P54028, p()=2.2E-13, pid=43%.
 
 
 0.999
rpl21e
Ribosomal protein L21; Function Code:10.04 - Metabolism of Macromolecules, Ribosomal proteins; similar to, sp:LN:RL21_METJA AC:P54013, p()=8E-25, pid=50%; Belongs to the eukaryotic ribosomal protein eL21 family.
  
 0.999
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.