STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_140Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, gp:GI:g1786498 LN:ECAE000137, p()=5.8E-38, pid=25%. (396 aa)    
Predicted Functional Partners:
MTH_1850
Fumarate reductase; Function Code:1.02 - Carbohydrate Metabolism, Citrate cycle (TCA cycle); similar to, sp:LN:Y092_METJA AC:Q57557, p()=6.9E-106, pid=43%.
 
 0.994
MTH_139
Heterodisulfide reductase HdrD related protein; Function Code:1.02 - Carbohydrate Metabolism, Citrate cycle (TCA cycle); similar to, gp:GI:e290652:g1890198, p()=1.1E-23, pid=29%.
 
 
 0.959
pyrK
Cytochrome-c3 hydrogenase, gamma subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
  
   0.853
MTH_907
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, gp:GI:g1653116 LN:D90911, p()=4.7E-18, pid=26%.
  
   0.754
hdrA
Heterodisulfide reductase, subunit A; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B); Belongs to the HdrA family.
  
 
 0.723
MTH_1024
Rod shape-determining protein; Function Code:11.04 - Cell envelope, Murein sacculus and peptidoglycan; similar to, gp:GI:g142855, p()=4E-46, pid=29%.
   
   0.626
hdrB
Heterodisulfide reductase, subunit B; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B); Belongs to the HdrB family.
 
 
 0.605
hdrC
Heterodisulfide reductase, subunit C; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
  
 
0.541
mfnB
Conserved protein; Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).
       0.536
MTH_1856
Sodium/proline symporter (proline permease); Function Code:12.01 - Cell Processes, Transport of amino acids--peptides and amines; similar to, sp:LN:PANF_HAEIN AC:P44963, p()=6.9E-27, pid=29%; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
  
 0.533
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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