STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MTH_151Methyl coenzyme M reductase system, component A2 homolog; Function Code:2.02 - Energy Metabolism, Methane metabolism; similar to, pir:LN:D64507 AC:D64507, p()=2.5E-140, pid=51%. (590 aa)    
Predicted Functional Partners:
MTH_153
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:C64366 AC:C64366, p()=1.6E-19, pid=38%.
  
  
 0.941
MTH_152
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, gp_new:GI:e311284:g1929333 LN:BSZ93767, p()=8.6E-12, pid=27%; Belongs to the flavoredoxin family.
       0.788
MTH_132
Cobalt transport protein Q; Function Code:12.05 - Cell Processes, Transport of cations; similar to, gp:GI:e237184:g1419077, p()=2.3E-91, pid=67%.
  
 
 0.785
MTH_1705
Cobalt transport membrane protein; Function Code:12.05 - Cell Processes, Transport of cations; similar to, pir:LN:B64496 AC:B64496, p()=1E-15, pid=20%.
  
 
 0.785
MTH_453
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:B64496 AC:B64496, p()=0.00012, pid=23%.
  
 
 0.785
mtrH
N5-methyl-tetrahydromethanopterin:coenzyme M methyltransferase, subunit H; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. MtrH catalyzes the transfer of the methyl group from methyl-tetrahydromethanopterin to the corrinoid prosthetic group of MtrA.
  
  
  0.784
MTH_154
Unknown; Function Code:14.00 - Unknown; similar to, sp:LN:VA17_VACCV AC:P16711, p()=0.14, pid=12%.
       0.768
mcrC
Methyl coenzyme M reductase I, C protein; Function Code:2.02 - Energy Metabolism, Methane metabolism; similar to, gp:GI:g517429 LN:MTU10036, p()=1.3E-102, pid=99%.
   
 
 0.761
MTH_1870
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:B64400 AC:B64400, p()=4.2E-19, pid=31%.
   
 
 0.744
mrtA
Methyl coenzyme M reductase II, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
    
 
 0.717
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.