Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MTH_153Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:C64366 AC:C64366, p()=1.6E-19, pid=38%. (131 aa)    
Predicted Functional Partners:
MTH_151
Methyl coenzyme M reductase system, component A2 homolog; Function Code:2.02 - Energy Metabolism, Methane metabolism; similar to, pir:LN:D64507 AC:D64507, p()=2.5E-140, pid=51%.
  
  
 0.941
MTH_152
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, gp_new:GI:e311284:g1929333 LN:BSZ93767, p()=8.6E-12, pid=27%; Belongs to the flavoredoxin family.
     
 0.788
MTH_154
Unknown; Function Code:14.00 - Unknown; similar to, sp:LN:VA17_VACCV AC:P16711, p()=0.14, pid=12%.
       0.773
MTH_149
Molybdenum cofactor biosynthesis protein MoaE; Function Code:9.11 - Metabolism of Cofactors and Vitamins, Molybdopterin; similar to, gp:GI:g1825695, p()=2.5E-10, pid=28%.
  
  
 0.643
MTH_150
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:E64367 AC:E64367, p()=7.6E-52, pid=54%; Belongs to the archaeal NMN adenylyltransferase family.
     
 0.572
MTH_740
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:IMDH_METKA AC:P50100, p()=6.8E-12, pid=43%.
  
  
 0.569
sod
Superoxide dismutase (Fe/Mn); Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.557
ogt
O6-methylguanidine-DNA methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
  
  
 0.519
MTH_157
Flavoprotein A homolog (III); Function Code:13.07 - Other, Unclassified; similar to, pir:LN:S66533 AC:S66533, p()=4.1E-60, pid=68%.
  
  
 0.512
MTH_159
Alkyl hydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
  
 0.507
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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