STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfdAConserved protein; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. (141 aa)    
Predicted Functional Partners:
pfdB
Conserved protein; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
 
 0.999
rpl31e
Ribosomal protein L31; Function Code:10.04 - Metabolism of Macromolecules, Ribosomal proteins; similar to, sp:LN:RL31_METJA AC:P54009, p()=4.7E-20, pid=45%; Belongs to the eukaryotic ribosomal protein eL31 family.
 
  
 0.966
rpl18a
Ribosomal protein L18a; Function Code:10.04 - Metabolism of Macromolecules, Ribosomal proteins; similar to, sp:LN:RLX_METJA AC:P54052, p()=0.000000056, pid=39%.
  
  
 0.934
eif6
Conserved protein; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.
     
 0.930
MTH_1615
Conserved protein; DNA-binding protein which can interact with a randomly chosen 20-mer of double-stranded DNA.
  
   0.917
thsB
Chaperonin; Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity; Belongs to the TCP-1 chaperonin family.
  
 
 0.916
thsA
Chaperonin; Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity; Belongs to the TCP-1 chaperonin family.
   
 
 0.905
ftsY
Signal recognition particle protein (docking protein); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
 
     0.849
MTH_1614
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:B64386 AC:B64386, p()=1.1E-45, pid=47%.
       0.845
rnp4
Conserved protein; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
 
     0.797
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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