STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_1622Unknown; Function Code:14.00 - Unknown; similar to, sp:LN:YC32_METJA AC:Q58629, p()=0.00093, pid=17%. (125 aa)    
Predicted Functional Partners:
MTH_1648
Dihydrolipoamide dehydrogenase; Function Code:1.01 - Carbohydrate Metabolism, Glycolysis--Gluconeogenesis; similar to, pir:LN:D64379 AC:D64379, p()=8.1E-48, pid=31%.
  
 
 0.722
MTH_1096
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, gp:GI:g1653922 LN:D90917, p()=0.0000055, pid=14%.
   
 
 0.693
MTH_1903
Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:e284341:g1771850, p()=0.00029, pid=17%.
  
 0.682
MTH_1621
GTP-binding protein, GTP1/OBG family; Function Code:13.07 - Other, Unclassified; similar to, pir:LN:E64465 AC:E64465, p()=1.8E-107, pid=51%.
  
    0.586
thi4
Thiamine biosynthetic enzyme; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
       0.560
MTH_740
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:IMDH_METKA AC:P50100, p()=6.8E-12, pid=43%.
 
    0.499
guaAB
GMP synthetase, subunit B; Catalyzes the synthesis of GMP from XMP.
  
 
 0.419
MTH_992
Inosine-5'-monophosphate dehydrogenase related protein IX; Function Code:4.01 - Nucleotide Metabolism, Purine metabolism; similar to, pir:LN:B48868 AC:B48868, p()=1.9E-16, pid=14%.
 
    0.418
ribH
Riboflavin synthase beta subunit; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
 
 0.415
MTH_1225
Inosine-5'-monophosphate dehydrogenase related protein IV; Function Code:4.01 - Nucleotide Metabolism, Purine metabolism; similar to, pir:LN:H64452 AC:H64452, p()=1.2E-11, pid=21%.
 
     0.413
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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