node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MTH_1013 | MTH_167 | MTH_1013 | MTH_167 | Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, gp:GI:e288126:g1752671, p()=1E-13, pid=25%. | S-adenosyl-L-methionine uroporphyrinogen methyltransferase; Function Code:9.10 - Metabolism of Cofactors and Vitamins, Porphyrin and chlorophyll metabolism; similar to, pir:LN:A42471 AC:A42471, p()=5.9E-84, pid=64%; Belongs to the precorrin methyltransferase family. | 0.996 |
MTH_1013 | MTH_602 | MTH_1013 | MTH_602 | Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, gp:GI:e288126:g1752671, p()=1E-13, pid=25%. | Precorrin-3 methylase; Function Code:9.10 - Metabolism of Cofactors and Vitamins, Porphyrin and chlorophyll metabolism; similar to, pir:LN:A64497 AC:A64497, p()=3.3E-74, pid=58%. | 0.741 |
MTH_1013 | hemA | MTH_1013 | MTH_1012 | Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, gp:GI:e288126:g1752671, p()=1E-13, pid=25%. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.928 |
MTH_1013 | hemB | MTH_1013 | MTH_744 | Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, gp:GI:e288126:g1752671, p()=1E-13, pid=25%. | Porphobilinogen synthase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity). | 0.543 |
MTH_1013 | hemC | MTH_1013 | MTH_874 | Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, gp:GI:e288126:g1752671, p()=1E-13, pid=25%. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0.709 |
MTH_1013 | hemD | MTH_1013 | MTH_166 | Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, gp:GI:e288126:g1752671, p()=1E-13, pid=25%. | Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.896 |
MTH_164 | MTH_167 | MTH_164 | MTH_167 | Single-stranded DNA exonuclease RecJ related protein; Function Code:10.11 - Metabolism of Macromolecules, DNA degradation--restriction/modification; similar to, pir:LN:A64422 AC:A64422, p()=4.9E-57, pid=32%. | S-adenosyl-L-methionine uroporphyrinogen methyltransferase; Function Code:9.10 - Metabolism of Cofactors and Vitamins, Porphyrin and chlorophyll metabolism; similar to, pir:LN:A42471 AC:A42471, p()=5.9E-84, pid=64%; Belongs to the precorrin methyltransferase family. | 0.785 |
MTH_164 | hemD | MTH_164 | MTH_166 | Single-stranded DNA exonuclease RecJ related protein; Function Code:10.11 - Metabolism of Macromolecules, DNA degradation--restriction/modification; similar to, pir:LN:A64422 AC:A64422, p()=4.9E-57, pid=32%. | Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.854 |
MTH_164 | purC | MTH_164 | MTH_170 | Single-stranded DNA exonuclease RecJ related protein; Function Code:10.11 - Metabolism of Macromolecules, DNA degradation--restriction/modification; similar to, pir:LN:A64422 AC:A64422, p()=4.9E-57, pid=32%. | Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Function Code:4.01 - Nucleotide Metabolism, Purine metabolism; similar to, pir:LN:G64498 AC:G64498, p()=1.6E-65, pid=46%; Belongs to the SAICAR synthetase family. | 0.598 |
MTH_164 | purQ | MTH_164 | MTH_168 | Single-stranded DNA exonuclease RecJ related protein; Function Code:10.11 - Metabolism of Macromolecules, DNA degradation--restriction/modification; similar to, pir:LN:A64422 AC:A64422, p()=4.9E-57, pid=32%. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.598 |
MTH_164 | srp19 | MTH_164 | MTH_165 | Single-stranded DNA exonuclease RecJ related protein; Function Code:10.11 - Metabolism of Macromolecules, DNA degradation--restriction/modification; similar to, pir:LN:A64422 AC:A64422, p()=4.9E-57, pid=32%. | Signal recognition particle 19 kDa protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP. | 0.876 |
MTH_167 | MTH_1013 | MTH_167 | MTH_1013 | S-adenosyl-L-methionine uroporphyrinogen methyltransferase; Function Code:9.10 - Metabolism of Cofactors and Vitamins, Porphyrin and chlorophyll metabolism; similar to, pir:LN:A42471 AC:A42471, p()=5.9E-84, pid=64%; Belongs to the precorrin methyltransferase family. | Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, gp:GI:e288126:g1752671, p()=1E-13, pid=25%. | 0.996 |
MTH_167 | MTH_164 | MTH_167 | MTH_164 | S-adenosyl-L-methionine uroporphyrinogen methyltransferase; Function Code:9.10 - Metabolism of Cofactors and Vitamins, Porphyrin and chlorophyll metabolism; similar to, pir:LN:A42471 AC:A42471, p()=5.9E-84, pid=64%; Belongs to the precorrin methyltransferase family. | Single-stranded DNA exonuclease RecJ related protein; Function Code:10.11 - Metabolism of Macromolecules, DNA degradation--restriction/modification; similar to, pir:LN:A64422 AC:A64422, p()=4.9E-57, pid=32%. | 0.785 |
MTH_167 | MTH_602 | MTH_167 | MTH_602 | S-adenosyl-L-methionine uroporphyrinogen methyltransferase; Function Code:9.10 - Metabolism of Cofactors and Vitamins, Porphyrin and chlorophyll metabolism; similar to, pir:LN:A42471 AC:A42471, p()=5.9E-84, pid=64%; Belongs to the precorrin methyltransferase family. | Precorrin-3 methylase; Function Code:9.10 - Metabolism of Cofactors and Vitamins, Porphyrin and chlorophyll metabolism; similar to, pir:LN:A64497 AC:A64497, p()=3.3E-74, pid=58%. | 0.628 |
MTH_167 | hemA | MTH_167 | MTH_1012 | S-adenosyl-L-methionine uroporphyrinogen methyltransferase; Function Code:9.10 - Metabolism of Cofactors and Vitamins, Porphyrin and chlorophyll metabolism; similar to, pir:LN:A42471 AC:A42471, p()=5.9E-84, pid=64%; Belongs to the precorrin methyltransferase family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.762 |
MTH_167 | hemB | MTH_167 | MTH_744 | S-adenosyl-L-methionine uroporphyrinogen methyltransferase; Function Code:9.10 - Metabolism of Cofactors and Vitamins, Porphyrin and chlorophyll metabolism; similar to, pir:LN:A42471 AC:A42471, p()=5.9E-84, pid=64%; Belongs to the precorrin methyltransferase family. | Porphobilinogen synthase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity). | 0.835 |
MTH_167 | hemC | MTH_167 | MTH_874 | S-adenosyl-L-methionine uroporphyrinogen methyltransferase; Function Code:9.10 - Metabolism of Cofactors and Vitamins, Porphyrin and chlorophyll metabolism; similar to, pir:LN:A42471 AC:A42471, p()=5.9E-84, pid=64%; Belongs to the precorrin methyltransferase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0.988 |
MTH_167 | hemD | MTH_167 | MTH_166 | S-adenosyl-L-methionine uroporphyrinogen methyltransferase; Function Code:9.10 - Metabolism of Cofactors and Vitamins, Porphyrin and chlorophyll metabolism; similar to, pir:LN:A42471 AC:A42471, p()=5.9E-84, pid=64%; Belongs to the precorrin methyltransferase family. | Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.999 |
MTH_167 | purC | MTH_167 | MTH_170 | S-adenosyl-L-methionine uroporphyrinogen methyltransferase; Function Code:9.10 - Metabolism of Cofactors and Vitamins, Porphyrin and chlorophyll metabolism; similar to, pir:LN:A42471 AC:A42471, p()=5.9E-84, pid=64%; Belongs to the precorrin methyltransferase family. | Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Function Code:4.01 - Nucleotide Metabolism, Purine metabolism; similar to, pir:LN:G64498 AC:G64498, p()=1.6E-65, pid=46%; Belongs to the SAICAR synthetase family. | 0.797 |
MTH_167 | purQ | MTH_167 | MTH_168 | S-adenosyl-L-methionine uroporphyrinogen methyltransferase; Function Code:9.10 - Metabolism of Cofactors and Vitamins, Porphyrin and chlorophyll metabolism; similar to, pir:LN:A42471 AC:A42471, p()=5.9E-84, pid=64%; Belongs to the precorrin methyltransferase family. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.807 |