STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_1698Delta 1-pyrroline-5-carboxylate synthetase; Function Code:5.09 - L-Amino Acid Metabolism, Arginine and proline metabolism; similar to, pir:LN:B64357 AC:B64357, p()=9.6E-29, pid=34%. (228 aa)    
Predicted Functional Partners:
MTH_834
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:H64404 AC:H64404, p()=5.9E-61, pid=40%.
 
  
 0.986
mfnB
Conserved protein; Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).
 
   
 0.871
MTH_835
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:G64401 AC:G64401, p()=5.4E-19, pid=38%.
 
   
 0.871
MTH_1741
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:Y107_METJA AC:Q57571, p()=1.5E-108, pid=44%.
 
   
 0.851
ef1b
Translation elongation factor EF-1b; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA; Belongs to the EF-1-beta/EF-1-delta family.
       0.839
pth
Conserved protein; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
       0.806
MTH_1557
Tungsten formylmethanofuran dehydrogenase, subunit A; Function Code:2.02 - Energy Metabolism, Methane metabolism; similar to, pir:LN:S57456 AC:S57456, p()=0, pid=94%.
 
   
 0.794
MTH_743
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:Y227_METJA AC:Q57680, p()=1.7E-45, pid=37%.
 
   
 0.730
ehaS
Formylmethanofuran:tetrahydromethanopterin formyltransferase II; Function Code:2.02 - Energy Metabolism, Methane metabolism; similar to, sp:LN:FTR_METTH AC:P21348, p()=1.6E-44, pid=36%; Belongs to the FTR family.
 
     0.725
ftr
Formylmethanofuran:tetrahydromethanopterin formyltransferase; Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR); Belongs to the FTR family.
 
     0.724
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.