STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_1715Phycocyanin alpha phycocyanobilin lyase CpcE related protein; Function Code:9.10 - Metabolism of Cofactors and Vitamins, Porphyrin and chlorophyll metabolism; similar to, gp:GI:e266604:g1546897, p()=0.000000035, pid=11%. (449 aa)    
Predicted Functional Partners:
eif5a
Translation initiation factor, eIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
 
 0.966
MTH_1716
Unknown; Function Code:14.00 - Unknown; similar to, pir:LN:S33341 AC:S33341, p()=0.9, pid=07%.
       0.603
MTH_1717
Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:g1707007 LN:ATU78721, p()=0.81, pid=06%.
       0.563
dys
Deoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
  
 
 0.536
MTH_1585
O-linked GlcNAc transferase; Function Code:10.02 - Metabolism of Macromolecules, Transcription--mRNA synthesis and modification (includes regulators); similar to, pir:LN:H64467 AC:H64467, p()=1.3E-22, pid=82%.
 
 
 0.510
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
  
   0.509
rps8e
Ribosomal protein S8; Function Code:10.04 - Metabolism of Macromolecules, Ribosomal proteins; similar to, sp:LN:RS8E_METJA AC:P54055, p()=6.2E-34, pid=51%.
   
    0.508
MTH_1214
pre-mRNA splicing protein PRP31; Function Code:10.02 - Metabolism of Macromolecules, Transcription--mRNA synthesis and modification (includes regulators); similar to, pir:LN:F64386 AC:F64386, p()=6.1E-43, pid=23%.
   
  
 0.506
rpl10
Ribosomal protein Lp0 (E.coli); Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
   
  
 0.497
guaAB
GMP synthetase, subunit B; Catalyzes the synthesis of GMP from XMP.
  
    0.493
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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