STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tgtAtRNA-guanine transglycosylase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. (665 aa)    
Predicted Functional Partners:
nac
Conserved protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.
 
     0.948
MTH_178
Icc related protein; Function Code:10.02 - Metabolism of Macromolecules, Transcription--mRNA synthesis and modification (includes regulators); similar to, gp:GI:g699231 LN:MLU15182, p()=1.8E-14, pid=28%.
  
    0.934
MTH_1665
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:E64427 AC:E64427, p()=3.6E-38, pid=33%.
 
  
0.874
MTH_175
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:F64383 AC:F64383, p()=1.4E-41, pid=27%.
     
 0.870
MTH_179
Unknown; Function Code:14.00 - Unknown; similar to, pir:LN:D64435 AC:D64435, p()=0.17, pid=09%.
       0.863
MTH_180
Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:e310271:g1914213, p()=0.98, pid=03%.
       0.863
MTH_1414
protein-L-isoaspartate methyltransferase homolog; Function Code:10.08 - Metabolism of Macromolecules, Protein translation and modification; similar to, sp:LN:Y134_METJA AC:Q57598, p()=1.3E-43, pid=43%.
  
  
 0.853
truB
Centromere/microtubule-binding protein; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
  
  
 0.803
MTH_1885
Sodium-dependent phosphate transporter; Function Code:12.04 - Cell Processes, Transport of anions; similar to, pir:LN:S08522 AC:S08522, p()=1.2E-60, pid=48%.
  
    0.800
MTH_547
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, gp:GI:g1881240 LN:AB001488, p()=2E-28, pid=28%.
   
 
 0.800
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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