Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MTH_178Icc related protein; Function Code:10.02 - Metabolism of Macromolecules, Transcription--mRNA synthesis and modification (includes regulators); similar to, gp:GI:g699231 LN:MLU15182, p()=1.8E-14, pid=28%. (196 aa)    
Predicted Functional Partners:
MTH_179
Unknown; Function Code:14.00 - Unknown; similar to, pir:LN:D64435 AC:D64435, p()=0.17, pid=09%.
 
     0.879
MTH_180
Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:e310271:g1914213, p()=0.98, pid=03%.
       0.862
nac
Conserved protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.
       0.845
tgtA
tRNA-guanine transglycosylase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family.
  
    0.837
MTH_175
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:F64383 AC:F64383, p()=1.4E-41, pid=27%.
       0.514
pgk2
2-phosphoglycerate kinase; Function Code:1.01 - Carbohydrate Metabolism, Glycolysis--Gluconeogenesis; similar to, pir:LN:S41582 AC:S41582, p()=1.2E-115, pid=69%.
 
     0.502
cpgS
Unknown; Catalyzes the formation of cyclic 2,3-diphosphoglycerate (cDPG) by formation of an intramolecular phosphoanhydride bond at the expense of ATP. Not able to catalyze cDPG hydrolysis. May be involved in osmotic balance.
       0.502
MTH_181
Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:e306628:g1877178, p()=0.28, pid=14%.
       0.428
argJ
Glutamate N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
     
 0.405
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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