STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_1803Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:Y037_METJA AC:Q60344, p()=7.6E-20, pid=25%. (247 aa)    
Predicted Functional Partners:
MTH_1802
ATP-dependent helicase; Function Code:10.02 - Metabolism of Macromolecules, Transcription--mRNA synthesis and modification (includes regulators); similar to, sp:LN:Y294_METJA AC:Q57742, p()=9.5E-196, pid=13%; Belongs to the helicase family.
 
    0.941
MTH_1804
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:YWAB_BACSU AC:P39582, p()=0.000018, pid=14%.
       0.773
lig
DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
 
   
 0.709
MTH_312
ATP-dependent helicase; Function Code:10.02 - Metabolism of Macromolecules, Transcription--mRNA synthesis and modification (includes regulators); similar to, gp:GI:e283825:g1707782, p()=3E-34, pid=27%.
 
    0.578
MTH_1325
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:Y038_METJA AC:Q60345, p()=2.3E-43, pid=46%.
  
     0.537
dnaG
Conserved protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
 
     0.516
MTH_1302
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:Y106_METJA AC:Q57570, p()=1.3E-31, pid=30%.
  
     0.493
MTH_1805
Unknown; Function Code:14.00 - Unknown; similar to, pir:LN:B48521 AC:B48521:A48521, p()=0.45, pid=16%.
       0.458
cdc6-1
Cdc6 related protein; Involved in regulation of DNA replication. May play an essential role in origin recognition. Binds to DNA, with a preference for origin-specific double-stranded sequences. Does not bind single- stranded DNA. Inhibits MCM helicase activity but does not affect its oligomeric state. Belongs to the CDC6/cdc18 family.
  
     0.414
MTH_1407
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:B64477 AC:B64477, p()=1.5E-14, pid=35%; Belongs to the UPF0147 family.
  
     0.407
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.