STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_189Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:g1498542 LN:HSU64486, p()=0.08, pid=18%. (60 aa)    
Predicted Functional Partners:
pdxT
Conserved protein; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
       0.773
MTH_191
Glutamine PRPP amidotransferase; Function Code:4.01 - Nucleotide Metabolism, Purine metabolism; similar to, sp:LN:PUR1_SYNP7 AC:Q55038, p()=1.7E-21, pid=22%.
       0.773
MTH_192
Tungsten formylmethanofuran dehydrogenase, subunit C homolog; Function Code:2.02 - Energy Metabolism, Methane metabolism; similar to, pir:LN:B64446 AC:B64446, p()=0.0000024, pid=20%.
       0.757
MTH_193
Coenzyme F420-reducing hydrogenase, beta subunit homolog; Function Code:2.02 - Energy Metabolism, Methane metabolism; similar to, sp:LN:FRHB_METJA AC:Q60341, p()=3.3E-35, pid=31%.
       0.757
MTH_194
Glutamate synthase (NADPH), alpha subunit; Function Code:5.01 - L-Amino Acid Metabolism, Alanine--aspartate and glutamate metabolism; similar to, pir:LN:F64468 AC:F64468, p()=2.2E-90, pid=42%; Belongs to the glutamate synthase family.
       0.731
mdh
Lactate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
       0.526
MTH_187
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, gp:GI:g1651830 LN:D90900, p()=1.6E-12, pid=82%.
       0.512
MTH_195
Efflux pump antibiotic resistance protein; Function Code:12.11 - Cell Processes, Detoxification; similar to, gp:GI:e264148:g1524267, p()=6.2E-41, pid=24%.
       0.447
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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