STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdxTConserved protein; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (192 aa)    
Predicted Functional Partners:
pdxS
Ethylene-inducible protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.
 0.999
MTH_191
Glutamine PRPP amidotransferase; Function Code:4.01 - Nucleotide Metabolism, Purine metabolism; similar to, sp:LN:PUR1_SYNP7 AC:Q55038, p()=1.7E-21, pid=22%.
       0.884
MTH_404
Ribokinase; Function Code:1.03 - Carbohydrate Metabolism, Pentose phosphate cycle; similar to, sp:LN:RBSK_HAEIN AC:P44331, p()=1.1E-20, pid=27%; Belongs to the carbohydrate kinase PfkB family.
    
 0.834
rpiA
Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
     
 0.806
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P).
    
  0.804
MTH_1584
Phosphomannomutase; Function Code:1.05 - Carbohydrate Metabolism, Fructose and mannose metabolism; similar to, gp:GI:g1272329 LN:MTU51624, p()=1.3E-88, pid=38%; Belongs to the phosphohexose mutase family.
     
  0.800
MTH_192
Tungsten formylmethanofuran dehydrogenase, subunit C homolog; Function Code:2.02 - Energy Metabolism, Methane metabolism; similar to, pir:LN:B64446 AC:B64446, p()=0.0000024, pid=20%.
       0.790
MTH_193
Coenzyme F420-reducing hydrogenase, beta subunit homolog; Function Code:2.02 - Energy Metabolism, Methane metabolism; similar to, sp:LN:FRHB_METJA AC:Q60341, p()=3.3E-35, pid=31%.
       0.780
MTH_189
Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:g1498542 LN:HSU64486, p()=0.08, pid=18%.
       0.773
MTH_194
Glutamate synthase (NADPH), alpha subunit; Function Code:5.01 - L-Amino Acid Metabolism, Alanine--aspartate and glutamate metabolism; similar to, pir:LN:F64468 AC:F64468, p()=2.2E-90, pid=42%; Belongs to the glutamate synthase family.
     
 0.762
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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