STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_193Coenzyme F420-reducing hydrogenase, beta subunit homolog; Function Code:2.02 - Energy Metabolism, Methane metabolism; similar to, sp:LN:FRHB_METJA AC:Q60341, p()=3.3E-35, pid=31%. (352 aa)    
Predicted Functional Partners:
frhG
Coenzyme F420-reducing hydrogenase, gamma subunit; Reduces the physiological low-potential two-electron acceptor coenzyme F420, and the artificial one-electron acceptor methylviologen; Belongs to the FrhG family.
 0.987
frhA
Coenzyme F420-reducing hydrogenase, alpha subunit; Reduces the physiological low-potential two-electron acceptor coenzyme F420, and the artificial one-electron acceptor methylviologen; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
  
 0.981
MTH_192
Tungsten formylmethanofuran dehydrogenase, subunit C homolog; Function Code:2.02 - Energy Metabolism, Methane metabolism; similar to, pir:LN:B64446 AC:B64446, p()=0.0000024, pid=20%.
  
    0.974
mer
Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase; Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT.
 
 
 0.955
frhD
Coenzyme F420-reducing hydrogenase, delta subunit; Function Code:2.02 - Energy Metabolism, Methane metabolism; similar to, sp:LN:FRHD_METTH AC:P19497, p()=5.9E-84, pid=95%.
  
 
 0.932
frhB
Coenzyme F420-reducing hydrogenase, beta subunit; Reduces the physiological low-potential two-electron acceptor coenzyme F420, and the artificial one-electron acceptor methylviologen; Belongs to the FrhB family.
  
  
0.926
MTH_341
Coenzyme F420-reducing hydrogenase, beta subunit homolog; Function Code:2.02 - Energy Metabolism, Methane metabolism; similar to, pir:LN:D35620 AC:D35620, p()=1.8E-21, pid=19%.
  
  
 
0.923
mtd
Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin dehydrogenase; Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.
   
 
 0.922
MTH_194
Glutamate synthase (NADPH), alpha subunit; Function Code:5.01 - L-Amino Acid Metabolism, Alanine--aspartate and glutamate metabolism; similar to, pir:LN:F64468 AC:F64468, p()=2.2E-90, pid=42%; Belongs to the glutamate synthase family.
  
  
 0.861
MTH_191
Glutamine PRPP amidotransferase; Function Code:4.01 - Nucleotide Metabolism, Purine metabolism; similar to, sp:LN:PUR1_SYNP7 AC:Q55038, p()=1.7E-21, pid=22%.
 
    0.858
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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