STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_204Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:YGFA_ECOLI AC:P09160, p()=0.00076, pid=12%. (338 aa)    
Predicted Functional Partners:
MTH_205
Hydrogenase expression/formation protein HypE; Function Code:2.02 - Energy Metabolism, Methane metabolism; similar to, pir:LN:D64384 AC:D64384, p()=3.2E-92, pid=45%.
       0.755
MTH_548
Sensory transduction regulatory protein; Function Code:12.12 - Cell Processes, Broad regulatory functions; similar to, gp:GI:g1652473 LN:D90905, p()=1.2E-23, pid=18%.
  
 
 0.698
MTH_206
Unknown; Function Code:14.00 - Unknown; similar to, gp_new:GI:e315172:g2078069, p()=0.75, pid=21%.
       0.664
MTH_252
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, gp:GI:g809710, p()=0.00000051, pid=16%.
  
    0.655
MTH_806
Protease IV; Function Code:10.12 - Metabolism of Macromolecules, Degradation of proteins--peptides--and glycopeptides; similar to, sp:LN:Y651_METJA AC:Q58067, p()=2E-35, pid=28%.
  
  
 0.614
glnA
Glutamine synthetase; Probably involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
  
 
 0.600
rps8e
Ribosomal protein S8; Function Code:10.04 - Metabolism of Macromolecules, Ribosomal proteins; similar to, sp:LN:RS8E_METJA AC:P54055, p()=6.2E-34, pid=51%.
       0.511
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
    0.507
MTH_203
ATP-dependent RNA helicase, eIF-4A family; Function Code:10.07 - Metabolism of Macromolecules, Aminoacyl tRNA synthetases and tRNA modification; similar to, gp:GI:g1881268 LN:AB001488, p()=1.2E-83, pid=40%; Belongs to the DEAD box helicase family.
  
    0.482
MTH_1068
Conserved protein; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family.
 
     0.476
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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