Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rps8eRibosomal protein S8; Function Code:10.04 - Metabolism of Macromolecules, Ribosomal proteins; similar to, sp:LN:RS8E_METJA AC:P54055, p()=6.2E-34, pid=51%. (127 aa)    
Predicted Functional Partners:
rpl31e
Ribosomal protein L31; Function Code:10.04 - Metabolism of Macromolecules, Ribosomal proteins; similar to, sp:LN:RL31_METJA AC:P54009, p()=4.7E-20, pid=45%; Belongs to the eukaryotic ribosomal protein eL31 family.
  
 
 0.997
rps6e
Ribosomal protein S6; Function Code:10.04 - Metabolism of Macromolecules, Ribosomal proteins; similar to, sp:LN:RS6E_METJA AC:P54067, p()=4.9E-25, pid=41%; Belongs to the eukaryotic ribosomal protein eS6 family.
  
 
 0.997
rpl44e
Ribosomal protein L36a; Binds to the 23S rRNA.
  
 
 0.996
rpl22
Ribosomal protein L17 (E.coli); This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
   
 
 0.996
rpl21e
Ribosomal protein L21; Function Code:10.04 - Metabolism of Macromolecules, Ribosomal proteins; similar to, sp:LN:RL21_METJA AC:P54013, p()=8E-25, pid=50%; Belongs to the eukaryotic ribosomal protein eL21 family.
  
 
 0.995
rpl37ae
Ribosomal protein L37a; Binds to the 23S rRNA.
  
 
 0.995
rps4e
Ribosomal protein S4; Function Code:10.04 - Metabolism of Macromolecules, Ribosomal proteins; similar to, sp:LN:RS4E_METJA AC:P54039, p()=1.2E-60, pid=52%; Belongs to the eukaryotic ribosomal protein eS4 family.
  
 
 0.994
rps19e
Ribosomal protein S19; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family.
   
 
 0.994
rpl3
Ribosomal protein L3 (E.coli); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
  
 
 0.994
rps24e
Ribosomal protein S24; Function Code:10.04 - Metabolism of Macromolecules, Ribosomal proteins; similar to, sp:LN:RS24_HALMA AC:P19953, p()=0.00000001, pid=21%; Belongs to the eukaryotic ribosomal protein eS24 family.
  
 
 0.994
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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