STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_213Ferrous iron transport protein B; Function Code:12.05 - Cell Processes, Transport of cations; similar to, pir:LN:F64370 AC:F64370, p()=1.1E-80, pid=32%. (638 aa)    
Predicted Functional Partners:
MTH_1362
Unknown; Function Code:14.00 - Unknown; similar to, sp:LN:FEOA_ECOLI AC:P33649, p()=0.002, pid=20%.
  
  
 0.838
MTH_214
Iron repressor; Function Code:10.02 - Metabolism of Macromolecules, Transcription--mRNA synthesis and modification (includes regulators); similar to, gp:GI:g1171107 LN:MTU14191, p()=2.3E-20, pid=29%.
  
  
 0.752
MTH_212
Exodeoxyribonuclease; Involved in DNA uracil repair. Recognizes DNA uracil residues within double-stranded DNA and initiates DNA-U repair by endonucleotic incision on the 5'-side of the 2'-d-uridine residue, irrespective of the nature of the opposing nucleotide. In addition, acts as an apurinic/apyrimidinic (AP) endonuclease hydrolyzing the DNA phosphodiester backbone immediately at the 5'-side of AP sites, and as a 3'-5' exonuclease. Strongly binds to double-stranded DNA.
       0.585
MTH_215
FUN34 related protein; Function Code:13.0=7 - Other, Unclassified; similar to, sp:LN:YAAH_ECOLI AC:P28695, p()=1.1E-34, pid=38%.
       0.454
MTH_216
acetyl-CoA synthetase; Function Code:1.08 - Carbohydrate Metabolism, Pyruvate and acetyl-CoA metabolism; similar to, pir:LN:B47682 AC:B47682, p()=7.6E-11, pid=47%.
     
 0.429
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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