STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
MTH_217acetyl-CoA synthetase; Function Code:1.08 - Carbohydrate Metabolism, Pyruvate and acetyl-CoA metabolism; similar to, gp:GI:g1001254, p()=1E-159, pid=52%. (558 aa)    
Predicted Functional Partners:
MTH_1726
Citrate synthase I; Function Code:1.02 - Carbohydrate Metabolism, Citrate cycle (TCA cycle); similar to, sp:LN:CYSZ_CUCMA AC:P49299, p()=1.6E-15, pid=28%.
  
 0.961
MTH_962
Citrate synthase I; Function Code:1.02 - Carbohydrate Metabolism, Citrate cycle (TCA cycle); similar to, sp:LN:CYSZ_CUCMA AC:P49299, p()=6.4E-16, pid=30%.
  
 0.961
MTH_793
Lipid-transfer protein (sterol or nonspecific); Function Code:3.04 - Lipid Metabolism, Sterol biosynthesis; similar to, pir:LN:D64493 AC:D64493, p()=3.1E-126, pid=63%.
  
 
 0.956
leuA
Isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate).
  
 
 0.931
aksA
2-isopropylmalate synthase; Catalyzes the condensation of alpha-ketoglutarate and acetyl- CoA to form trans-homoaconitate. Can also catalyze the condensation of alpha-ketoadipate with acetyl-CoA to form (R)-homo(2)citrate, and the condensation of alpha-ketopimelate with acetyl-CoA to form (R)- homo(3)citrate (By similarity); Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.931
korA
2-oxoglutarate oxidoreductase, alpha subunit; Function Code:2.08 - Energy Metabolism, Electron transport; similar to, pir:LN:E64334 AC:E64334, p()=3.6E-116, pid=57%.
  
 
 0.929
porB
Pyruvate oxidoreductase, beta subunit; Function Code:2.08 - Energy Metabolism, Electron transport; similar to, pir:LN:C64333 AC:C64333, p()=4.6E-109, pid=66%.
  
 
 0.925
porC
Pyruvate oxidoreductase, gamma subunit; Function Code:2.08 - Energy Metabolism, Electron transport; similar to, pir:LN:F64333 AC:F64333, p()=3.7E-52, pid=42%.
  
 
 0.924
korB
2-oxoglutarate oxidoreductase, beta subunit; Function Code:2.08 - Energy Metabolism, Electron transport; similar to, pir:LN:A64367 AC:A64367, p()=2.1E-88, pid=54%.
  
 
 0.921
cdhE
Corrinoid/iron-sulfur protein, large subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2).
   
 
 0.921
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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