STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_220Flavoprotein A homolog (II); Function Code:13.07 - Other, Unclassified; similar to, pir:LN:D64393 AC:D64393, p()=8.2E-142, pid=62%. (410 aa)    
Predicted Functional Partners:
MTH_1354
NADH oxidase; Function Code:9.04 - Metabolism of Cofactors and Vitamins, Nicotinate and nicotinamide metabolism (NADP); similar to, pir:LN:A64381 AC:A64381, p()=5E-126, pid=54%.
    
 0.895
MTH_757
Rubredoxin oxidoreductase; Function Code:2.08 - Energy Metabolism, Electron transport; similar to, gp:GI:e258466:g1491677, p()=1.4E-34, pid=51%; Belongs to the desulfoferrodoxin family.
 
  
 0.658
MTH_219
Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:g1166464 LN:NGU19579, p()=0.97, pid=12%.
       0.632
cofD
Conserved protein; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
     
 0.534
cofC
Conserved protein; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family.
      
 0.524
thsA
Chaperonin; Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity; Belongs to the TCP-1 chaperonin family.
     
 0.490
MTH_221
Unknown; Function Code:14.00 - Unknown; similar to, sp:LN:FER2_DESDN AC:P00211, p()=0.48, pid=05%.
       0.448
MTH_1689
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:YG03_HAEIN AC:P44271, p()=5.9E-10, pid=23%; Belongs to the UPF0111 family.
  
    0.435
hcp
6Fe-6S prismane-containing protein; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
 
  
 0.428
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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