STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_231Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:B64471 AC:B64471, p()=3.1E-32, pid=37%; Belongs to the MtxX family. (242 aa)    
Predicted Functional Partners:
uppS
Conserved protein; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
  
    0.864
MTH_233
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:E64497 AC:E64497, p()=8.6E-44, pid=36%.
       0.800
mtrH
N5-methyl-tetrahydromethanopterin:coenzyme M methyltransferase, subunit H; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. MtrH catalyzes the transfer of the methyl group from methyl-tetrahydromethanopterin to the corrinoid prosthetic group of MtrA.
     
 0.591
MTH_1098
Bacteriochlorophyll synthase related protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
      
 0.535
nifD
Nitrogenase NifD subunit; This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.
      
 0.531
nifH2
Nitrogenase NifH subunit; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
      
 0.531
MTH_1014
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:Y115_METJA AC:Q57579, p()=2.5E-37, pid=39%.
      
 0.530
MTH_1015
Methyl coenzyme M reductase system, component A2; Function Code:2.02 - Energy Metabolism, Methane metabolism; similar to, gp:GI:g293151, p()=2.7E-278, pid=93%.
      
 0.530
mcrA
Methyl coenzyme M reductase I, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
      
 0.530
nifH1
Nitrogenase NifH subunit; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
      
 0.530
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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