STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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uppSConserved protein; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids. (255 aa)    
Predicted Functional Partners:
idsA
Bifunctional short chain isoprenyl diphosphate synthase; Function Code:3.01 - Lipid Metabolism, Fatty acid biosynthesis; similar to, sp:LN:IDSA_METTH AC:Q53479, p()=1.4E-130, pid=78%.
 
 
 0.987
MTH_233
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:E64497 AC:E64497, p()=8.6E-44, pid=36%.
     
 0.892
MTH_231
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:B64471 AC:B64471, p()=3.1E-32, pid=37%; Belongs to the MtxX family.
  
    0.882
MTH_1808
Phytoene synthase; Function Code:9.14 - Metabolism of Cofactors and Vitamins, Terpenoid biosynthesis (isomeric hydrocarbon ((C5H8)n); similar to, gp:GI:g1928932 LN:MMU92075, p()=1E-24, pid=29%.
  
 
 0.852
MTH_735
phospho-N-acetylmuramoyl-pentapeptide- transferase; Function Code:11.04 - Cell envelope, Murein sacculus and peptidoglycan; similar to, sp:LN:MRAY_BACSU AC:Q03521, p()=1.4E-11, pid=11%; Belongs to the glycosyltransferase 4 family. MraY subfamily.
 
  
 0.845
pyrH
Uridine monophosphate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
  
 0.823
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
 
  
 0.802
MTH_1368
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:C64421 AC:C64421, p()=2.1E-14, pid=23%.
  
  
 0.759
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
  
  
 0.751
glmM
Phosphomannomutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
 
   
 0.745
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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