STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uppSConserved protein; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids. (255 aa)    
Predicted Functional Partners:
idsA
Bifunctional short chain isoprenyl diphosphate synthase; Function Code:3.01 - Lipid Metabolism, Fatty acid biosynthesis; similar to, sp:LN:IDSA_METTH AC:Q53479, p()=1.4E-130, pid=78%.
 
 
 0.987
MTH_233
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:E64497 AC:E64497, p()=8.6E-44, pid=36%.
     
 0.885
pyrH
Uridine monophosphate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
  
 0.881
MTH_1368
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:C64421 AC:C64421, p()=2.1E-14, pid=23%.
  
  
 0.875
MTH_231
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:B64471 AC:B64471, p()=3.1E-32, pid=37%; Belongs to the MtxX family.
  
    0.864
MTH_1808
Phytoene synthase; Function Code:9.14 - Metabolism of Cofactors and Vitamins, Terpenoid biosynthesis (isomeric hydrocarbon ((C5H8)n); similar to, gp:GI:g1928932 LN:MMU92075, p()=1E-24, pid=29%.
  
 
 0.856
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
  
    0.729
nusA
Transcription termination factor NusA; Participates in transcription termination. Belongs to the NusA family.
  
    0.725
MTH_1217
Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:g929913, p()=0.26, pid=09%.
  
    0.725
rps2
Ribosomal protein Sa (E.coli); Function Code:10.04 - Metabolism of Macromolecules, Ribosomal proteins; similar to, sp:LN:RS2_METJA AC:P54109, p()=2.7E-63, pid=57%; Belongs to the universal ribosomal protein uS2 family.
  
  
 0.710
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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