STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_243Conserved protein; RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. Belongs to the HARP family. (220 aa)    
Predicted Functional Partners:
rnp3
Conserved protein; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
  
   
 0.873
MTH_246
Twitching mobility (PilT) related protein; Function Code:11.03 - Cell envelope, Surface proteins, glycoproteins, and structures; similar to, pir:LN:D64491 AC:D64491, p()=4.9E-133, pid=44%.
 
     0.857
MTH_1221
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:F64351 AC:F64351, p()=4.4E-72, pid=40%.
 
     0.822
hisS
histidyl-tRNA synthetase; Function Code:10.07 - Metabolism of Macromolecules, Aminoacyl tRNA synthetases and tRNA modification; similar to, sp:LN:SYH_METJA AC:Q58406, p()=8.8E-90, pid=40%; Belongs to the class-II aminoacyl-tRNA synthetase family.
       0.808
hisI
phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP; Belongs to the PRA-CH family.
       0.795
rnp2
Conserved protein; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
      
 0.783
MTH_247
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:YD11_METJA AC:Q58707, p()=3.3E-26, pid=32%.
       0.780
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
       0.519
MTH_1356
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:F64404 AC:F64404, p()=4.2E-35, pid=36%.
  
     0.500
fno
Conserved protein; Catalyzes the reduction of NADP(+) with F420H(2) via hydride transfer, and likely the reverse reaction, i.e. the reduction of F420 with NADPH. Probably functions in the regeneration of NADPH required in biosynthetic reactions. Is specific for reduced F420 as electron donor for the reduction of NADP; neither reduced FAD nor FMN can act as electron donor. The enzyme is also specific for NADP; NAD is not utilized as substrate; Belongs to the F420-dependent NADP reductase family.
       0.496
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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