Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MTH_273Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:YBHB_ECOLI AC:P12994, p()=8.2E-23, pid=38%; Belongs to the UPF0098 family. (151 aa)    
Predicted Functional Partners:
rpl13/rps9
Ribosomal protein S16 (E.coli); L13 protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity).
  
 
 0.975
rpl2
Ribosomal protein L8 (E.coli); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
   
 
 0.866
rps10
Ribosomal protein S20 (E.coli); Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
   
 
 0.862
rps2
Ribosomal protein Sa (E.coli); Function Code:10.04 - Metabolism of Macromolecules, Ribosomal proteins; similar to, sp:LN:RS2_METJA AC:P54109, p()=2.7E-63, pid=57%; Belongs to the universal ribosomal protein uS2 family.
  
 
 0.862
rps5
Ribosomal protein S2 (E.coli); With S4 and S12 plays an important role in translational accuracy.
   
 
 0.854
rpl15
Ribosomal protein L27a (E.coli); Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
   
 
 0.852
rpl3
Ribosomal protein L3 (E.coli); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
 
 0.849
rpl22
Ribosomal protein L17 (E.coli); This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
  
 
 0.849
rpl10e
Ribosomal protein L10; Function Code:10.04 - Metabolism of Macromolecules, Ribosomal proteins; similar to, pir:LN:G64367 AC:G64367, p()=2.3E-50, pid=53%; Belongs to the universal ribosomal protein uL16 family.
   
 
 0.846
rps11
Ribosomal protein S14 (E.coli); Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family.
   
 
 0.841
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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