STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_287Anaerobic ribonucleoside-triphosphate reductase activating protein; Function Code:4.01 - Nucleotide Metabolism, Purine metabolism; similar to, sp:LN:NRDG_BPT4 AC:P07075, p()=3.1E-16, pid=22%. (237 aa)    
Predicted Functional Partners:
MTH_1539
Anaerobic ribonucleoside-triphosphate reductase; Function Code:4.01 - Nucleotide Metabolism, Purine metabolism; similar to, pir:LN:H64403 AC:H64403, p()=2.5E-200, pid=51%.
 
 
 0.937
queD
Conserved protein; Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde.
  
  
 0.834
MTH_288
Unknown; Function Code:14.00 - Unknown; similar to, sp:LN:SINI_BACSU AC:P23308, p()=0.89, pid=04%.
       0.773
MTH_289
Unknown; Function Code:14.00 - Unknown; similar to, pir:LN:C64162 AC:C64162, p()=0.996, pid=03%.
       0.773
queC
Conserved protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
  
  
 0.763
MTH_286
Unknown; Function Code:14.00 - Unknown.
       0.732
MTH_345
Pyruvate formate-lyase 2 activating enzyme; Function Code:1.08 - Carbohydrate Metabolism, Pyruvate and acetyl-CoA metabolism; similar to, gp:GI:g1787045 LN:ECAE000184, p()=2.7E-31, pid=28%.
 
   
 0.632
MTH_284
ATP-dependent Clp protease regulatory subunit; Function Code:10.12 - Metabolism of Macromolecules, Degradation of proteins--peptides--and glycopeptides; similar to, sp:LN:CLAB_LYCES AC:P31542, p()=2.3E-53, pid=22%.
  
  
 0.602
MTH_346
Formate acetyltransferase 2; Function Code:1.08 - Carbohydrate Metabolism, Pyruvate and acetyl-CoA metabolism; similar to, sp:LN:PFLD_ECOLI AC:P32674, p()=3.7E-21, pid=23%.
 
   
 0.600
tgtA
tRNA-guanine transglycosylase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family.
     
 0.593
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.