Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MTH_296Unknown; Function Code:14.00 - Unknown; similar to, sp:LN:KC2B_CAEEL AC:P28548, p()=0.9, pid=08%. (419 aa)    
Predicted Functional Partners:
MTH_297
DNA-dependent RNA polymerase, subunit A; Function Code:10.02 - Metabolism of Macromolecules, Transcription--mRNA synthesis and modification (includes regulators); similar to, sp:LN:RPA1_METTH AC:P09846, p()=6.2E-48, pid=68%.
       0.675
MTH_298
DNA-dependent RNA polymerase, subunit A; Function Code:10.02 - Metabolism of Macromolecules, Transcription--mRNA synthesis and modification (includes regulators); similar to, sp:LN:RPA1_METTH AC:P09846, p()=6.7E-40, pid=77%.
       0.675
MTH_299
DNA-dependent RNA polymerase, subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
       0.675
MTH_300
Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:g642348, p()=0.51, pid=14%.
       0.468
MTH_301
Unknown; Function Code:14.00 - Unknown; similar to, sp:LN:SCOT_CAEEL AC:Q09450, p()=0.98, pid=13%.
       0.401
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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