Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MTH_307Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:YF65_METJA AC:Q58960, p()=2.2E-77, pid=34%. (479 aa)    
Predicted Functional Partners:
MTH_306
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:E64457 AC:E64457, p()=2.1E-09, pid=18%.
   
 
 0.932
MTH_543
Unknown; Function Code:14.00 - Unknown; similar to, pir:LN:A56858 AC:A56858, p()=0.95, pid=11%.
   
 
 0.774
rad50
Intracellular protein transport protein; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily.
     
 0.769
MTH_308
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:YPV9_METTF AC:P29586, p()=1.2E-19, pid=30%.
       0.576
MTH_1741
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:Y107_METJA AC:Q57571, p()=1.5E-108, pid=44%.
 
     0.569
infB
Translation initiation factor IF2 homolog; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 (By similarity).
   
   0.508
MTH_305
Unknown; Function Code:14.00 - Unknown; similar to, pir:LN:B64493 AC:B64493, p()=0.002, pid=09%.
     
 0.501
MTH_304
Unknown; Function Code:14.00 - Unknown; similar to, pir:LN:C64493 AC:C64493, p()=0.0047, pid=11%.
       0.485
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.