Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
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[Homology]
Score
MTH_312ATP-dependent helicase; Function Code:10.02 - Metabolism of Macromolecules, Transcription--mRNA synthesis and modification (includes regulators); similar to, gp:GI:e283825:g1707782, p()=3E-34, pid=27%. (702 aa)    
Predicted Functional Partners:
MTH_311
Unknown; Function Code:14.00 - Unknown; similar to, pir:LN:I61696 AC:I61696, p()=0.71, pid=05%.
  
 0.928
MTH_1803
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:Y037_METJA AC:Q60344, p()=7.6E-20, pid=25%.
 
    0.621
MTH_310
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:YZ36_METJA AC:Q60257, p()=0.0000011, pid=13%.
       0.612
MTH_314
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:E64388 AC:E64388, p()=7.6E-31, pid=19%.
  
  
 0.596
MTH_313
Transcriptional regulator; Function Code:10.02 - Metabolism of Macromolecules, Transcription--mRNA synthesis and modification (includes regulators); similar to, sp:LN:YYBA_BACSU AC:P37503, p()=2.2E-13, pid=25%.
  
    0.580
lig
DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
 
    0.533
uvrC
Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
  
  
 0.502
MTH_309
Unknown; Function Code:14.00 - Unknown; similar to, sp:LN:MT_GADMO AC:P51902, p()=0.88, pid=02%.
       0.422
radB
DNA repair protein Rad51 homolog; Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange (By similarity).
  
 
 0.420
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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