STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_312ATP-dependent helicase; Function Code:10.02 - Metabolism of Macromolecules, Transcription--mRNA synthesis and modification (includes regulators); similar to, gp:GI:e283825:g1707782, p()=3E-34, pid=27%. (702 aa)    
Predicted Functional Partners:
MTH_311
Unknown; Function Code:14.00 - Unknown; similar to, pir:LN:I61696 AC:I61696, p()=0.71, pid=05%.
  
 0.931
MTH_310
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:YZ36_METJA AC:Q60257, p()=0.0000011, pid=13%.
       0.612
MTH_314
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:E64388 AC:E64388, p()=7.6E-31, pid=19%.
     
 0.608
MTH_313
Transcriptional regulator; Function Code:10.02 - Metabolism of Macromolecules, Transcription--mRNA synthesis and modification (includes regulators); similar to, sp:LN:YYBA_BACSU AC:P37503, p()=2.2E-13, pid=25%.
  
    0.591
MTH_1803
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:Y037_METJA AC:Q60344, p()=7.6E-20, pid=25%.
 
    0.578
lig
DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
 
    0.543
radA
DNA repair protein RadA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules (By similarity).
  
 
 0.519
radB
DNA repair protein Rad51 homolog; Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange (By similarity).
  
 
 0.519
uvrC
Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
  
    0.457
MTH_1185
Translation elongation factor, EF-1 alpha related protein; Function Code:10.08 - Metabolism of Macromolecules, Protein translation and modification; similar to, gp:GI:g1916927 LN:MMU87965, p()=1.1E-68, pid=30%.
   
 
 0.448
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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