STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_327Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:g1336313 LN:HIVU57152, p()=0.96, pid=07%. (261 aa)    
Predicted Functional Partners:
MTH_325
Unknown; Function Code:14.00 - Unknown; similar to, pir:LN:C64508 AC:C64508, p()=0.076, pid=10%.
   
 
 0.984
MTH_1082
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:F64508 AC:F64508, p()=5.3E-52, pid=25%.
   
 
 0.983
MTH_326
Unknown; Function Code:14.00 - Unknown.
       0.808
MTH_328
Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:g1061376 LN:PAU38364, p()=0.999, pid=09%.
       0.808
MTH_323
Unknown; Function Code:14.00 - Unknown; similar to, pir:LN:I51906 AC:I51906, p()=0.1, pid=04%.
       0.805
MTH_324
Unknown; Function Code:14.00 - Unknown; similar to, pir:LN:A61448 AC:A61448, p()=0.83, pid=25%.
       0.805
cas2
Conserved protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Involved in the integration of spacer DNA into the CRISPR cassette (By similarity). Functions as a ssRNA-specific endoribonuclease.
     
 0.535
MTH_1091
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:G64346 AC:G64346, p()=5.8E-38, pid=41%.
     
 0.535
MTH_329
Unknown; Function Code:14.00 - Unknown; similar to, pir:LN:JQ0136, p()=0.9995, pid=07%.
       0.439
cas3
Conserved protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Cas3 plus Cascade participate in CRISPR interference, the third stage of CRISPR immunity. Anneals and unwinds R-loops (in which crRNA binds the target DNA, displacing the noncom [...]
     
 0.437
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.