Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
MTH_334Perosamine synthetase; Function Code:11.04 - Cell envelope, Murein sacculus and peptidoglycan; similar to, gp:GI:g1911763 LN:S83460, p()=3.8E-89, pid=45%; Belongs to the DegT/DnrJ/EryC1 family. (363 aa)    
Predicted Functional Partners:
gmd
GDP-D-mannose dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
  
 
 0.983
MTH_336
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:F64450 AC:F64450, p()=0.00066, pid=17%.
  
  
 0.848
MTH_332
LPS biosynthesis RfbU related protein; Function Code:11.04 - Cell envelope, Murein sacculus and peptidoglycan; similar to, pir:LN:H64446 AC:H64446, p()=4.5E-18, pid=22%.
  
  
 0.827
MTH_335
Galactosyl-transferase RfpB related protein; Function Code:11.04 - Cell envelope, Murein sacculus and peptidoglycan; similar to, pir:LN:H64446 AC:H64446, p()=2.9E-15, pid=16%.
  
  
 0.827
MTH_337
Unknown; Function Code:14.00 - Unknown.
       0.773
MTH_272
Acetyl / acyl transferase related protein; Function Code:3.01 - Lipid metabolism, Fatty acid biosynthesis; similar to, gp:GI:g992972, p()=2E-12, pid=39%.
  
  
 0.691
MTH_836
UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase; Function Code:11.04 - Cell envelope, Murein sacculus and peptidoglycan; similar to, gp:GI:g1773354 LN:SAU81973, p()=6.7E-76, pid=38%; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
  
  
 0.680
MTH_331
Mannosyltransferase; Function Code:11.04 - Cell envelope, Murein sacculus and peptidoglycan; similar to, gp:GI:g1652563 LN:D90906, p()=2.5E-16, pid=24%.
  
  
 0.665
MTH_875
3-chlorobenzoate-3,4-dioxygenase dyhydrogenase related protein; Function Code:13.07 - Other, Unclassified; similar to, gp:GI:g1001423, p()=5.8E-38, pid=31%.
  
  
 0.629
MTH_837
UDP-N-acetylglucosamine 2-epimerase; Function Code:11.04 - Cell envelope, Murein sacculus and peptidoglycan; similar to, pir:LN:G64487 AC:G64487, p()=3.2E-85, pid=38%.
  
  
 0.628
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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