STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_336Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:F64450 AC:F64450, p()=0.00066, pid=17%. (173 aa)    
Predicted Functional Partners:
MTH_334
Perosamine synthetase; Function Code:11.04 - Cell envelope, Murein sacculus and peptidoglycan; similar to, gp:GI:g1911763 LN:S83460, p()=3.8E-89, pid=45%; Belongs to the DegT/DnrJ/EryC1 family.
  
  
 0.861
gmd
GDP-D-mannose dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
     
 0.828
MTH_332
LPS biosynthesis RfbU related protein; Function Code:11.04 - Cell envelope, Murein sacculus and peptidoglycan; similar to, pir:LN:H64446 AC:H64446, p()=4.5E-18, pid=22%.
   
 
 0.811
MTH_335
Galactosyl-transferase RfpB related protein; Function Code:11.04 - Cell envelope, Murein sacculus and peptidoglycan; similar to, pir:LN:H64446 AC:H64446, p()=2.9E-15, pid=16%.
   
 
 0.811
MTH_337
Unknown; Function Code:14.00 - Unknown.
       0.773
gpsA
Glycerol-3-phosphate dehydrogenase (NAD); Function Code:8.01 - Metabolism of Complex Lipids, Glycerolipid metabolism; similar to, sp:LN:GPDA_BACSU AC:P46919, p()=3.5E-31, pid=30%; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
   
   0.677
mre11
Rad32 related protein; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family.
  
  
 0.673
glmS
Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
 
 0.576
MTH_331
Mannosyltransferase; Function Code:11.04 - Cell envelope, Murein sacculus and peptidoglycan; similar to, gp:GI:g1652563 LN:D90906, p()=2.5E-16, pid=24%.
  
  
 0.554
MTH_836
UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase; Function Code:11.04 - Cell envelope, Murein sacculus and peptidoglycan; similar to, gp:GI:g1773354 LN:SAU81973, p()=6.7E-76, pid=38%; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
 
  
 0.554
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.