STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_345Pyruvate formate-lyase 2 activating enzyme; Function Code:1.08 - Carbohydrate Metabolism, Pyruvate and acetyl-CoA metabolism; similar to, gp:GI:g1787045 LN:ECAE000184, p()=2.7E-31, pid=28%. (288 aa)    
Predicted Functional Partners:
MTH_346
Formate acetyltransferase 2; Function Code:1.08 - Carbohydrate Metabolism, Pyruvate and acetyl-CoA metabolism; similar to, sp:LN:PFLD_ECOLI AC:P32674, p()=3.7E-21, pid=23%.
  
 0.989
MTH_1539
Anaerobic ribonucleoside-triphosphate reductase; Function Code:4.01 - Nucleotide Metabolism, Purine metabolism; similar to, pir:LN:H64403 AC:H64403, p()=2.5E-200, pid=51%.
 
  
 0.798
MTH_347
O-antigen transporter; Function Code:12.02 - Cell Processes, Transport of carbohydrates organic acids alcohols and lipids; similar to, gp:GI:g1736727 LN:D90841, p()=4.1E-53, pid=28%.
       0.779
MTH_344
UDP-galactopyranose mutase; Function Code:11.04 - Cell envelope, Murein sacculus and peptidoglycan; similar to, sp:LN:GLF_MYCPN AC:P75499, p()=3.3E-51, pid=32%.
       0.772
MTH_287
Anaerobic ribonucleoside-triphosphate reductase activating protein; Function Code:4.01 - Nucleotide Metabolism, Purine metabolism; similar to, sp:LN:NRDG_BPT4 AC:P07075, p()=3.1E-16, pid=22%.
 
   
 0.632
MTH_976
Pyruvate formate-lyase activating enzyme related protein; Function Code:2.08 - Energy Metabolism, Electron transport; similar to, gp:GI:g1016358, p()=6.6E-14, pid=23%.
  
     0.629
MTH_343
Rhamnosyl transferase; Function Code:11.04 - Cell envelope, Murein sacculus and peptidoglycan; similar to, gp:GI:g765062, p()=1.8E-18, pid=27%.
     
 0.627
MTH_348
Rhamnosyl transferase; Function Code:11.04 - Cell envelope, Murein sacculus and peptidoglycan; similar to, gp:GI:g557194, p()=0.000000023, pid=21%.
     
 0.604
MTH_984
1,3-propanediol dehydrogenase; Function Code:13.07 - Other, Unclassified; similar to, sp:LN:YIAY_ECOLI AC:P37686, p()=4.5E-70, pid=42%.
  
  
 0.579
MTH_1586
Pyruvate formate-lyase activating enzyme; Function Code:2.08 - Energy Metabolism, Electron transport; similar to, pir:LN:B64453 AC:B64453, p()=7.4E-38, pid=37%.
  
     0.551
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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