Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MTH_359Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, gp:GI:e283907:g1707725, p()=2.3E-09, pid=06%. (534 aa)    
Predicted Functional Partners:
MTH_360
Sensory transduction histidine kinase; Function Code:12.12 - Cell Processes, Broad regulatory functions; similar to, gp:GI:g1652472 LN:D90905, p()=8.8E-35, pid=12%.
       0.454
MTH_358
Gluthatione-regulated K+/H+ antiporter; Function Code:12.05 - Cell Processes, Transport of cations; similar to, sp:LN:KEFX_HAEIN AC:P44933, p()=2.3E-50, pid=27%.
       0.422
MTH_179
Unknown; Function Code:14.00 - Unknown; similar to, pir:LN:D64435 AC:D64435, p()=0.17, pid=09%.
  
     0.410
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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