STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gpsAGlycerol-3-phosphate dehydrogenase (NAD); Function Code:8.01 - Metabolism of Complex Lipids, Glycerolipid metabolism; similar to, sp:LN:GPDA_BACSU AC:P46919, p()=3.5E-31, pid=30%; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (321 aa)    
Predicted Functional Partners:
egsA
Glycerol 1-phosphate dehydrogenase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. Is also able to catalyze the reverse reaction, i.e. the NAD(P)(+)-dependent oxidation of G1P but not of G3P. Is not active toward glycerol, dihydroxyacetone, glyceraldehyde-3-phosphate, glyceraldehyde and glycerol-2-phosphate; Belongs to the glycerol-1-phosphate dehydrogenase family.
    
 0.932
MTH_369
UDP-N-acetylglucosamine pyrophosphorylase related protein; Function Code:4.03 - Nucleotide Metabolism, Nucleotide sugars metabolism; similar to, pir:LN:D64437 AC:D64437, p()=0.00000091, pid=21%.
 
     0.847
gap
Glyceraldehyde 3-phosphate dehydrogenase; Function Code:1.01 - Carbohydrate Metabolism, Glycolysis--Gluconeogenesis; similar to, pir:LN:S02804 AC:S02804, p()=7.6E-139, pid=76%.
  
 
 0.767
MTH_367
O-antigen transporter; Function Code:12.02 - Cell Processes, Transport of carbohydrates organic acids alcohols and lipids; similar to, gp:GI:g1736727 LN:D90841, p()=2.7E-33, pid=26%.
     
 0.748
MTH_1347
Probable ATP-dependent helicase; Function Code:10.09 - Metabolism of macromolecules, DNA replication, modification, repair, and recombination; similar to, pir:LN:F64417 AC:F64417, p()=0.00025, pid=17%.
  
  
 0.720
MTH_336
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:F64450 AC:F64450, p()=0.00066, pid=17%.
   
   0.677
MTH_370
LPS biosynthesis RfbU related protein; Function Code:8.02 - Metabolism of Complex Lipids, Inositol phosphate metabolism; similar to, gp:GI:g1652478 LN:D90905, p()=7.1E-16, pid=25%.
  
  
 0.649
MTH_1577
Unknown; Function Code:14.00 - Unknown; similar to, sp:LN:YRUB_CLOPA AC:P23171, p()=0.000041, pid=21%.
  
  
 0.638
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
  
 0.614
ftsY
Signal recognition particle protein (docking protein); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
 
   
 0.608
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.