Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MTH_385Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:G64365 AC:G64365, p()=2E-37, pid=48%. (168 aa)    
Predicted Functional Partners:
MTH_387
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:F64365 AC:F64365, p()=0.000000003, pid=29%.
  
    0.980
MTH_388
Unknown; Function Code:14.00 - Unknown; similar to, pir:LN:E64365 AC:E64365, p()=0.00047, pid=16%.
  
    0.980
MTH_389
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:D64365 AC:D64365, p()=1.2E-46, pid=54%.
  
    0.978
MTH_386
Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:g546182 LN:S70134, p()=0.69, pid=16%; To M.jannaschii MJ0526.1.
  
    0.957
ehaA
Unknown; One of the integral membrane subunits of multisubunit membrane-bound [NiFe]-hydrogenase eha. Eha is predicted to form large electron transfer complex and might catalyze energy-driven reduction of low-potential redox carriers (By similarity).
  
  
 0.945
MTH_391
NADH dehydrogenase I, subunit N related protein; Function Code:2.01 - Oxidative phosphorylation; similar to, pir:LN:B64365 AC:B64365, p()=1.8E-25, pid=31%.
  
    0.896
MTH_390
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:C64365 AC:C64365, p()=8.4E-30, pid=48%.
  
    0.895
MTH_395
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:F64364 AC:F64364, p()=1.6E-12, pid=33%.
  
    0.828
MTH_396
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:E64364 AC:E64364, p()=2.8E-15, pid=32%.
  
    0.819
MTH_397
Formate hydrogenlyase, subunit 7; Function Code:2.02 - Energy Metabolism, Methane metabolism; similar to, pir:LN:D64364 AC:D64364, p()=3.8E-50, pid=63%.
  
    0.806
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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