Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MTH_402Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:e1226:g1364210, p()=0.8, pid=04%. (289 aa)    
Predicted Functional Partners:
ehaS
Formylmethanofuran:tetrahydromethanopterin formyltransferase II; Function Code:2.02 - Energy Metabolism, Methane metabolism; similar to, sp:LN:FTR_METTH AC:P21348, p()=1.6E-44, pid=36%; Belongs to the FTR family.
       0.849
MTH_404
Ribokinase; Function Code:1.03 - Carbohydrate Metabolism, Pentose phosphate cycle; similar to, sp:LN:RBSK_HAEIN AC:P44331, p()=1.1E-20, pid=27%; Belongs to the carbohydrate kinase PfkB family.
       0.849
MTH_401
Polyferredoxin; Function Code:2.08 - Energy Metabolism, Electron transport; similar to, pir:LN:C37777 AC:C37777, p()=1.1E-24, pid=165%.
       0.780
MTH_400
Polyferredoxin; Function Code:2.08 - Energy Metabolism, Electron transport; similar to, sp:LN:NRFC_HAEIN AC:P45015, p()=0.00071, pid=10%.
       0.773
MTH_399
Polyferredoxin; Function Code:2.08 - Energy Metabolism, Electron transport; similar to, gp:GI:e286616:g1747410, p()=4.8E-17, pid=13%.
       0.687
MTH_397
Formate hydrogenlyase, subunit 7; Function Code:2.02 - Energy Metabolism, Methane metabolism; similar to, pir:LN:D64364 AC:D64364, p()=3.8E-50, pid=63%.
       0.628
MTH_398
Formate hydrogenlyase, subunit 5; Function Code:2.02 - Energy Metabolism, Methane metabolism; similar to, pir:LN:C64364 AC:C64364, p()=8.5E-92, pid=46%.
       0.628
MTH_395
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:F64364 AC:F64364, p()=1.6E-12, pid=33%.
       0.530
MTH_396
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:E64364 AC:E64364, p()=2.8E-15, pid=32%.
       0.530
MTH_394
Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:g1881338 LN:AB001488, p()=0.998, pid=16%.
       0.498
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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