Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MTH_404Ribokinase; Function Code:1.03 - Carbohydrate Metabolism, Pentose phosphate cycle; similar to, sp:LN:RBSK_HAEIN AC:P44331, p()=1.1E-20, pid=27%; Belongs to the carbohydrate kinase PfkB family. (298 aa)    
Predicted Functional Partners:
ehaS
Formylmethanofuran:tetrahydromethanopterin formyltransferase II; Function Code:2.02 - Energy Metabolism, Methane metabolism; similar to, sp:LN:FTR_METTH AC:P21348, p()=1.6E-44, pid=36%; Belongs to the FTR family.
     
 0.937
MTH_398
Formate hydrogenlyase, subunit 5; Function Code:2.02 - Energy Metabolism, Methane metabolism; similar to, pir:LN:C64364 AC:C64364, p()=8.5E-92, pid=46%.
     
 0.849
MTH_402
Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:e1226:g1364210, p()=0.8, pid=04%.
       0.849
hisA
Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Function Code:5.10 - L-Amino Acid Metabolism, Histidine metabolism; similar to, gp:GI:g150053, p()=1.1E-66, pid=44%.
  
  
 0.838
MTH_393
NADH dehydrogenase (ubiquinone), subunit 1 related protein; Function Code:2.01 - Energy Metabolism, Oxidative phosphorylation; similar to, pir:LN:H64364 AC:H64364, p()=6.8E-67, pid=46%.
     
 0.822
MTH_391
NADH dehydrogenase I, subunit N related protein; Function Code:2.01 - Oxidative phosphorylation; similar to, pir:LN:B64365 AC:B64365, p()=1.8E-25, pid=31%.
     
 0.809
ehaA
Unknown; One of the integral membrane subunits of multisubunit membrane-bound [NiFe]-hydrogenase eha. Eha is predicted to form large electron transfer complex and might catalyze energy-driven reduction of low-potential redox carriers (By similarity).
     
 0.800
ftr
Formylmethanofuran:tetrahydromethanopterin formyltransferase; Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR); Belongs to the FTR family.
     
 0.757
MTH_1237
NADH dehydrogenase (ubiquinone), subunit 1 related protein; Function Code:2.01 - Energy Metabolism, Oxidative phosphorylation; similar to, pir:LN:A64470 AC:A64470, p()=2.1E-47, pid=33%.
      
 0.753
MTH_1239
Formate hydrogenlyase, subunit 7; Function Code:2.02 - Energy Metabolism, Methane metabolism; similar to, pir:LN:B64470 AC:B64470, p()=9.7E-52, pid=64%.
      
 0.753
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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