Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MTH_412Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, gp:GI:e283907:g1707725, p()=0.000000042, pid=05%. (583 aa)    
Predicted Functional Partners:
MTH_965
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:YXEQ_BACSU AC:P54956, p()=1.1E-25, pid=27%.
 
   
 0.668
MTH_1448
Signal peptidase; Function Code:12.09 - Cell Processes, Protein and peptide secretion; similar to, sp:LN:SPC3_CANFA AC:P13679, p()=0.000000008, pid=24%.
  
  
 0.666
thsA
Chaperonin; Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity; Belongs to the TCP-1 chaperonin family.
     
 0.630
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
     
 0.629
MTH_1858
Phage infection protein homolog; Function Code:13.07 - Other, Unclassified; similar to, pir:LN:A48653 AC:A48653, p()=4.2E-41, pid=40%.
     
 0.628
mrtG
Methyl coenzyme M reductase II, gamma subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
      
 0.627
atpC
ATP synthase, subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane.
     
 0.623
mtrC
N5-methyl-tetrahydromethanopterin:coenzyme M methyltransferase, subunit C; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
      
 0.618
mtrD
N5-methyl-tetrahydromethanopterin:coenzyme M methyltransferase, subunit D; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
      
 0.618
mtrE
N5-methyl-tetrahydromethanopterin:coenzyme M methyltransferase, subunit E; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
      
 0.618
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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