Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MTH_413Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:Y282_METJA AC:Q57730, p()=8.6E-28, pid=43%. (130 aa)    
Predicted Functional Partners:
MTH_414
Asparagine synthetase; Function Code:5.01 - L-Amino Acid Metabolism, Alanine--aspartate and glutamate metabolism; similar to, sp:LN:ASNH_METJA AC:Q58516, p()=6.4E-73, pid=39%.
       0.764
MTH_415
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:Y243_METJA AC:Q57694, p()=0.000000092, pid=37%.
       0.483
MTH_417
Homoserine dehydrogenase homolog; Function Code:5.02 - L-Amino Acid Metabolism, Glycine--serine and threonine metabolism; similar to, pir:LN:A64500 AC:A64500, p()=2.1E-79, pid=49%.
     
 0.438
MTH_416
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:H64499 AC:H64499, p()=3.4E-17, pid=25%.
       0.436
apgM2
Phosphonopyruvate decarboxylase related protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
       0.404
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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