STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_414Asparagine synthetase; Function Code:5.01 - L-Amino Acid Metabolism, Alanine--aspartate and glutamate metabolism; similar to, sp:LN:ASNH_METJA AC:Q58516, p()=6.4E-73, pid=39%. (469 aa)    
Predicted Functional Partners:
pyrB
Aspartate carbamoyltransferase; Function Code:4.02 - Nucleotide Metabolism, Pyrimidine metabolism; similar to, pir:LN:D64497 AC:D64497, p()=3.7E-91, pid=54%.
  
 
 0.958
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.950
MTH_432
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:B64371 AC:B64371, p()=1.1E-57, pid=49%.
     0.949
argG
Argininosuccinate synthase; Function Code:5.01 - L-Amino Acid Metabolism, Alanine--aspartate and glutamate metabolism; similar to, sp:LN:ASSY_METJA AC:Q60174, p()=2.4E-135, pid=62%; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 0.933
MTH_1894
Aspartate aminotransferase homolog; Function Code:5.01 - L-Amino Acid Metabolism, Alanine--aspartate and glutamate metabolism; similar to, sp:LN:AAT_METJA AC:Q60317, p()=6.1E-82, pid=46%.
  
 
 0.925
MTH_802
Aspartokinase II alpha subunit; Function Code:5.01 - L-Amino Acid Metabolism, Alanine--aspartate and glutamate metabolism; similar to, gp:GI:e255104:g1770047 LN:BSZ75208, p()=1.4E-36, pid=29%; Belongs to the aspartokinase family.
  
 
 0.915
pyrI
Aspartate carbamoyltransferase regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase.
    
  0.905
mfnA
Glutamate decarboxylase; Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis; Belongs to the group II decarboxylase family. MfnA subfamily.
 
  
 0.867
nadX
Conserved protein; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
     
  0.800
MTH_413
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:Y282_METJA AC:Q57730, p()=8.6E-28, pid=43%.
       0.764
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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