STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_416Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:H64499 AC:H64499, p()=3.4E-17, pid=25%. (162 aa)    
Predicted Functional Partners:
MTH_417
Homoserine dehydrogenase homolog; Function Code:5.02 - L-Amino Acid Metabolism, Glycine--serine and threonine metabolism; similar to, pir:LN:A64500 AC:A64500, p()=2.1E-79, pid=49%.
       0.870
MTH_415
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:Y243_METJA AC:Q57694, p()=0.000000092, pid=37%.
       0.867
apgM2
Phosphonopyruvate decarboxylase related protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
       0.733
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
       0.572
MTH_414
Asparagine synthetase; Function Code:5.01 - L-Amino Acid Metabolism, Alanine--aspartate and glutamate metabolism; similar to, sp:LN:ASNH_METJA AC:Q58516, p()=6.4E-73, pid=39%.
       0.460
MTH_413
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:Y282_METJA AC:Q57730, p()=8.6E-28, pid=43%.
       0.436
carS
Conserved protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids.
       0.436
rps10
Ribosomal protein S20 (E.coli); Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
       0.424
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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