STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_435Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:Y209_METJA AC:Q57662, p()=1.1E-52, pid=47%. (248 aa)    
Predicted Functional Partners:
MTH_577
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:A64421 AC:A64421, p()=2.4E-32, pid=31%.
 
  
 0.985
MTH_1216
Function Code:9.05 - Metabolism of Cofactors and Vitamins, Pantothenate and CoA biosynthesis; similar to, pir:LN:A64414 AC:A64414, p()=6.1E-66, pid=38%.
 
  
 0.964
mfnA
Glutamate decarboxylase; Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis; Belongs to the group II decarboxylase family. MfnA subfamily.
    
 0.924
MTH_434
UMP/CMP kinase related protein; Function Code:4.02 - Nucleotide Metabolism, Pyrimidine metabolism; similar to, pir:LN:F64474 AC:F64474, p()=2.5E-30, pid=34%; Belongs to the UPF0200 family.
 
     0.912
MTH_433
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:C64495 AC:C64495, p()=5.7E-15, pid=31%; Belongs to the UPF0201 family.
 
   
 0.870
MTH_436
Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:g1652318 LN:D90904, p()=0.13, pid=17%.
       0.544
MTH_437
Endo-1,4-beta-glucanase; Function Code:7.02 - Metabolism of Complex Carbohydrates, Polysaccharde and starch metabolism polymers (glycogen--cellulose--starch); similar to, sp:LN:Y555_METJA AC:Q57975, p()=6.8E-99, pid=55%.
       0.544
cmk
Cytidylate kinase; Function Code:4.04 - Nucleotide Metabolism, Salvage and interconversion; similar to, pir:LN:H64381 AC:H64381, p()=5.2E-21, pid=32%.
  
    0.505
MTH_689
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:Y213_METJA AC:Q57666, p()=0.0000017, pid=26%.
 
   
 0.504
MTH_1768
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:H64505 AC:H64505, p()=1.4E-41, pid=30%.
 
     0.499
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.