Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MTH_439Recombinase; Function Code:10.09 - Metabolism of Macromolecules, DNA replication--modification--repair--and recombination; similar to, gp:GI:g1653852 LN:D90917, p()=1.7E-13, pid=44%. (238 aa)    
Predicted Functional Partners:
MTH_593
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:F64469 AC:F64469, p()=4.2E-12, pid=28%.
  
     0.689
MTH_1095
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, gp:GI:g1653851 LN:D90917, p()=0.000000003, pid=35%.
  
     0.688
MTH_440
Sensory transduction regulatory protein; Function Code:12.12 - Cell Processes, Broad regulatory functions; similar to, gp:GI:g1652473 LN:D90905, p()=2.1E-26, pid=15%.
     
 0.604
uvrC
Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
 
     0.433
MTH_438
Unknown; Function Code:14.00 - Unknown; similar to, sp:LN:YS45_CAEEL AC:Q09660, p()=0.26, pid=23%.
       0.430
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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