STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
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[Homology]
Score
MTH_445Sensory transduction regulatory protein; Function Code:12.12 - Cell Processes, Broad regulatory functions; similar to, gp:GI:g1001166, p()=2.5E-21, pid=33%. (145 aa)    
Predicted Functional Partners:
MTH_444
Sensory transduction histidine kinase; Function Code:12.12 - Cell Processes, Broad regulatory functions; similar to, gp:GI:g1001165, p()=1.2E-32, pid=19%.
 
   
 0.947
MTH_446
Sensory transduction regulatory protein; Function Code:12.12 - Cell Processes, Broad regulatory functions; similar to, gp:GI:g1652472 LN:D90905, p()=8.9E-39, pid=19%.
 
   
 0.799
MTH_457
Sensory transduction regulatory protein; Function Code:12.12 - Cell Processes, Broad regulatory functions; similar to, gp:GI:g1652473 LN:D90905, p()=1.5E-16, pid=07%.
 
 
 0.728
MTH_447
Sensory transduction regulatory protein; Function Code:12.12 - Cell Processes, Broad regulatory functions; similar to, gp:GI:g1652473 LN:D90905, p()=5.5E-26, pid=20%.
 
 
 0.672
MTH_458
Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:g1001841, p()=0.0032, pid=23%.
  
 
 0.549
uvrA
Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
     
 0.532
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
     
 0.456
MTH_902
Sensory transduction histidine kinase; Function Code:12.12 - Cell Processes, Broad regulatory functions; similar to, gp:GI:g1652472 LN:D90905, p()=1.7E-10, pid=10%.
   
 0.444
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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