Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MTH_447Sensory transduction regulatory protein; Function Code:12.12 - Cell Processes, Broad regulatory functions; similar to, gp:GI:g1652473 LN:D90905, p()=5.5E-26, pid=20%. (277 aa)    
Predicted Functional Partners:
MTH_457
Sensory transduction regulatory protein; Function Code:12.12 - Cell Processes, Broad regulatory functions; similar to, gp:GI:g1652473 LN:D90905, p()=1.5E-16, pid=07%.
 
 
0.924
MTH_458
Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:g1001841, p()=0.0032, pid=23%.
  
 
 0.909
MTH_444
Sensory transduction histidine kinase; Function Code:12.12 - Cell Processes, Broad regulatory functions; similar to, gp:GI:g1001165, p()=1.2E-32, pid=19%.
     0.895
MTH_446
Sensory transduction regulatory protein; Function Code:12.12 - Cell Processes, Broad regulatory functions; similar to, gp:GI:g1652472 LN:D90905, p()=8.9E-39, pid=19%.
   
 0.855
rpoD
DNA-dependent RNA polymerase, subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.847
rpoK
DNA-dependent RNA polymerase, subunit K; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family.
  
 
 0.826
MTH_902
Sensory transduction histidine kinase; Function Code:12.12 - Cell Processes, Broad regulatory functions; similar to, gp:GI:g1652472 LN:D90905, p()=1.7E-10, pid=10%.
 
 0.806
MTH_1240
Ferredoxin-like protein; Function Code:2.08 - Energy Metabolism, Electron transport; similar to, pir:LN:E64462 AC:E64462, p()=1.2E-30, pid=38%.
  
 
 0.794
rpoB2
DNA-dependent RNA polymerase, subunit B'; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. The B (B''+B' and beta) subunits have been implicated in DNA promoter recognition and also in nucleotide binding.
   
 
 0.793
rpoB1
DNA-dependent RNA polymerase, subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. The B (B''+B' and beta) subunits have been implicated in DNA promoter recognition and also in nucleotide binding.
   
 
 0.793
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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